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Welcome to oPOSSUM

A new version of oPOSSUM is available here: oPOSSUM 3

oPOSSUM is a web-based system for the detection of over-represented transcription factor binding sites in the promoters of sets of genes.

Human Single Site Analysis (SSA) is designed to detect over-represented conserved single sites in human and mouse genes.

Reference: Ho Sui, et al. (2005). oPOSSUM: Identification of over-represented transcription factor binding sites in co-expressed genes. NAR, 33(10):3154-64. PMID: 15933209

Human CSA (Module analysis) Enter >>

Human Combination Site Analysis (CSA) identifies over-represented combinations of conserved transcription factor binding sites in sets of human and mouse genes.

Reference: Huang, S., Fulton, D., et al. (2006). Identification of over-represented combinations of transcription factor binding sites in sets of co-expressed genes. In Advances in Bioinformatics and Computational Biology, Vol. 3. Imperial College Press, London, UK. 247-56. PDF.

Worm SSA Enter >>

Worm Single Site Analysis (SSA) identifies over-represented conserved transcription factor binding sites in sets of C. elegans and C. briggsae genes.

Yeast SSA Enter >>

Yeast Single Site Analysis (SSA) identifies over-represented transcription factor binding sites in sets of S. cerevisiae genes. Phylogenetic footprinting has not been used for yeast.

The first release of oPOSSUM single site analysis is available here.